RAB43 antibody

Catalog No. ABIN7118226

This anti-RAB43 antibody is a Rabbit Polyclonal antibody detecting RAB43 in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for RAB43 antibody (ABIN7118226)

Target: RAB43 (RAB43, Member RAS Oncogene Family (RAB43))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB43 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RAB43 Antibody

Purpose: RAB43 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: RAB43, member RAS oncogene family

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for RAB43

Target: RAB43 (RAB43, Member RAS Oncogene Family (RAB43))

Alternative Name: RAB43

Background:

Synonyms: Ras-related protein Rab-43|Ras-related protein Rab-41|RAB43|RAB41

Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.

Molecular Weight: 23 kDa

Gene ID: 339122

UniProt: Q86YS6